A Special Report in the October 2004 issue of the journal Pharmacogenomics is dedicated to Systems Literature Analysis and how this can be supported by Biovista’s BioLab Experiment Assistant tool.
Systems literature analysis (SLA) is the literature-driven version of systems biology. It treats collections of scientific literature as a system of millions of interconnections between research parameters, such as genes, diseases, tissues, cell events, model organisms, experiment types, and reagents. SLA aims to replace the traditional keyword-based querying of literature databases, which return sorted lists of papers, with a systems-based approach that returns integrated networks of relationships. Major applications include literature-based discovery of novel targets that link, for example, previously unlinked diseases and phenotypes to common genes and cellular events, and experiment design.
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