Mechanistic analysis of Atorvastatin

June 19, 2020COVID-19, Vizit Graphs

Repositioning of Atorvastatin for the treatment of COVID-19. Statins such as Atorvastatin are potent cholesterol-lowering drugs that are tested against COVID-19. Statins could be proven beneficial particularly against SARS-CoV-2-induced cardiovascular manifestations. Explore the live graph.

Mechanistic analysis of combination IFB-a2b chlorpheniramine, ibuprofen

June 19, 2020COVID-19, Vizit Graphs

Chlorphenamine is a known antihistamine used to treat the symptoms of allergic conditions such as allergic rhinitis, whereas Ibuprofen is a potent nonsteroidal anti-inflammatory drug (NSAID). Combination of Chlorpheniramine and ibuprofen combination have long been postulated to treat common cold and its symptoms. Role and efficacy in the COVID-19 remains to be elucidated. Explore the … Read More

Targeting the RAS system against COVID-19

June 19, 2020COVID-19, Vizit Graphs

There is growing amount of evidence to suggest the use of pharmaceuticals that target the Renin-Angiotensin System (e.g. angiotensin 1-7, ARBs and ACE inhibitors) may be beneficial in the treatment of COVID-19. This graph shows the interconnections among these classes of drugs, and SARS-CoV-2 via key genes implicated in this pathway. mediated. Explore the live … Read More

Administration of vitamin D could help fight COVID-19

June 19, 2020COVID-19, Vizit Graphs

Vitamin D supplementation has been shown to protect against SARS-COV-2 infection, and could be particularly helpful for patients that exhibit shortage of vitamin D (e.g. seniors, immunocompromised patients) leading to complications such as cardiovascular comorbidities. This graph explains the mechanism of action of vitamin D in COVID-19 via key genes implicated. Explore the live graph.