Repositioning of Atorvastatin for the treatment of COVID-19. Statins such as Atorvastatin are potent cholesterol-lowering drugs that are tested against COVID-19. Statins could be proven beneficial particularly against SARS-CoV-2-induced cardiovascular manifestations. Explore the live graph.
IMMUNITY
Mechanisms by which Eculizumab (Soliris) may benefit COVID-19 patients with respiratory distress syndrome
Eculizumab is a biologic therapy, a complement C5 inhibitor, and has recently shown promise in COVID-19. The graph provides an important step towards elucidating the MoA of this drug in COVID-19. Explore the live graph.
Mechanistic analysis of Ivermectin
Ivermectin is an anti-parasitic agent that has shown promise against the virus in vitro. Its potential mechanism of action (MoA) in COVID-19, is poorly understood. Explore the live graph.
Dexamethasone mechanism of action analysis in the treatment of SARS-COV-2 induced infections
Dexamethasone is a widely-used and safe steroid that has been studied in the context of treating viral respiratory disorders, and is THE FIRST drug that has been shown to reduce mortality of patients with severe COVID-19. Explore the live graph.
Lopinavir/Ritonavir mechanism of action analysis in COVID-19
Lopinavir/Ritonavir (Kaletra) is a combination of the antivirals Lopinavir and Ritonavir, that were originally designed to inhibit HIV from replicating by binding to the protease. Similarly, it has been postulated that the drug could also bind to the protease of SARS-CoV-2. The drug is currently being tested for the treatment of COVID-19. Explore the live … Read More