Repositioning of Atorvastatin for the treatment of COVID-19. Statins such as Atorvastatin are potent cholesterol-lowering drugs that are tested against COVID-19. Statins could be proven beneficial particularly against SARS-CoV-2-induced cardiovascular manifestations. Explore the live graph.
REVERSE TRANSCRIPTION
Pathways and cell types related to Amantadine’s MoA in COVID-19
Amantadine is an anti-viral drug which is also used in Parkinson’s disease. The drug has been shown to reduce viral load in the context of the influenza virus, and in the COVID-19 setting, it may be able to decrease the viral load in SARS-CoV-2 positive patients. Explore the live graph.
ACE2, TMPRSS2, Acute Lung Injury, ARDS, and Lung Fibrosis
The graph visualizes the relationships between genes ACE2 and TMPRSS2 and specific manifestations of COVID-19, such as Acute Lung Injury, ARDS and Lung Fibrosis through a network of specific biological entities such as Cell Types, Pathways and Anatomical Locations that are likely implicated in the pathogenesis of these disease symptoms. Explore the live graph.